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Individual patient eligibility for drug therapies available through Sesame are determined by the assessment of appropriateness of each therapy by the Sesame-listed provider and are subject to availability

Found in high concentrations in the male reproductive tract, L-carnitine is available through red meat, dairy, and fish, though supplementation may be necessary for those with low levels

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For short-term storage, refrigeration is acceptable

Combine with supportive nutrients like B vitamins and magnesium for neurological support

As expected, wild-type BoNT/X cleaved the VAMP1 fusion but showed no detectable activity on the procaspase-1 substrate (Extended Data Fig